Systemic Formulas JOT is a unique and comprehensive product for joint, disc and cartilage pain and degeneration. It contains Type II collagen, MSM, chondroitin sulfate and anti-inflammatory herbs to help cartilage integrity, joint lubrication and pain. Boswellia and Turmeric help with anti-inflammatory discomfort. Allow several months for maximum effectiveness in changing the health of the soft tissue. You’ll notice other improvements sooner.